Zapala is a city and touristic destination in the Patagonian province of Neuquén, Argentina with about 32,000 inhabitants according to the 2…Zapala is a city and touristic destination in the Patagonian province of Neuquén, Argentina with about 32,000 inhabitants according to the 2010 census. The city is located at the geographic center of the province at the confluence of national and provincial roads, on a route to the Andes and Chile. The city hosts a Loma Negra cement plant.