The show’s creators ruthlessly went after Kristi Noem’s appearance in the latest episode and depicted her Botox running out

Homeland Security Secretary Kristi Noem criticized “South Park,” stating it is “lazy to constantly make fun of women for how they look.”

In the episode, South Park Elementary guidance counselor Mr. Mackey gets fired due to the government "cutting back on unnecessary expenses" — a reference to the Trump administration and the Department of Government Efficiency's (DOGE) extensive cuts across the government.