At the time, the Oscar winner had to turn down the leading role as he was busy leading James Cameron’s ‘Titanic.’

Leonardo DiCaprio says the biggest regret of his acting career is turning down Paul Thomas Anderson's offer to star as the lead in 'Boogie Nights.'

An actor with such a high hit rate as Leonardo DiCaprio couldn’t possibly have any regrets, right? The man starred in Titanic, Inception, The Wolf of Wall Street, The Aviator, The Departed, and worked will nearly every major director at the height of their careers.