The San Francisco 49ers had a good start to their week of practice leading up to a Week 3 showdown with the Los Angeles Rams.

The San Francisco 49ers have the No. 1 seed and a bye in the first round of the NFL playoffs wrapped up heading into their Week 18 matchup with the Los Angeles Rams, so the team will not play ...

The San Francisco 49ers won’t have wide receiver Deebo Samuel for a couple weeks because of a calf injury he sustained late ...

SANTA CLARA, Calif. — The San Francisco 49ers have played games without Deebo Samuel Sr. in the last year and a half. And ...

The Los Angeles Rams haven’t had much of a home-field advantage at SoFi Stadium when the rival San Francisco 49ers come to ...

Here are eight stats and facts to know for Week 3 at SoFi Stadium. It’s been a tough start to the year for the Rams defense.

Now comes the hard part for Kyle Shanahan — devising a game plan without Deebo Samuel and Christian McCaffrey.

Just keep in mind a loss last year in Minnesota was part of the 49ers’ path to the Super Bowl: Without Deebo Samuel and ...

The San Francisco 49ers announced today that it’s the first NFL team to purchase sustainable aviation fuel (SAF). According ...

The San Francisco 49ers took their first loss of the season on Sunday, due in large part to a series of significant errors ...

The San Francisco 49ers look to bounce back after a surprising road loss as travel south to face their NFC West rivals, the ...

The 49ers woes in Minnesota continued last week when their former quarterback Sam Darnold torched his old squad. The offense ...