For decades, cancer immunotherapy has focused primarily on CD8 + cytotoxic T lymphocytes as the main executors of tumor cell killing. However, growing clinical and single-cell sequencing evidence ...

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by ...

A landmark study due to start in the coming months aims to test a method for rejuvenating our immune system in older age. The ...

Immune cells called double negative T cells are abundant in the intestine but have been poorly understood till date. In a recent study, researchers from the Institute of Science Tokyo report that ...

A research team from the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health has discovered how the ...

For some people, cancer immunotherapies are life-changing. These treatments can turn the body's own immune system against a tumor, either eliminating it or shrinking it enough to make surgery possible ...

Abnormal expansion of PD-1+ T lymphocytes may be a sign of lupus nephritis onset in patients with SLE. Elevated PD-1+CD4+ T cells represent an independent risk factor for lupus nephritis (LN) and may ...

New vaccine ‘could rejuvenate aging immune systems to tackle cancer and dementia’ - Researchers hope that resetting these cells may help the immune system regain characteristics of healthier immune ...

For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular ...