Integrins are transmembrane heterodimeric receptors that anchor cells to the extracellular matrix (ECM) and transduce signals in both directions across the plasma membrane. In tumours, integrin–ECM ...

The extracellular matrix (ECM) provides structural and biochemical support to cells, with a complex network of proteins such as fibrillins, elastins, fibulins and microfibril‐associated glycoproteins.

Researchers at Children's Hospital Los Angeles have discovered a key difference between the two main types of rhabdomyosarcoma—paving the way for more targeted treatments. The study, led by JinSeok ...

Skeletal muscles grow and regenerate as individual precursor cells—called myoblasts—fuse into long fibers from which mature ...

A new review in Molecular Biology Reports unifies how mechanobiological cues at cellular adhesions drive cytoskeletal ...

The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, extracellular matrix (ECM), cytokines, and growth factors, all interacting to ...

A three-cohort transcriptomic reanalysis finds extracellular-matrix remodeling as the most reproducible molecular signature ...

TB-500 has emerged as one of the more widely discussed synthetic peptides within regenerative and cellular research. Derived ...

The evolving landscape of peptide-based inquiry continues to uncover fragments that diverge meaningfully from their parent molecules, not by replicating their ...

Biomedical engineers at Duke University have developed a three-layer model of human blood vessels that enables researchers to ...