Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

As part of the body's first line of defense against foreign invaders, macrophages play an integral role in the innate immune ...

Researchers have identified an unexpected mechanism that links age-related stress to the decline of blood-forming stem cells. Instead of triggering cell death, a known signaling pathway subtly ...

Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...

A hallmark of type 2 diabetes is the progressive loss of beta cell mass: cells in the pancreas that produce and release ...

A newly discovered type of liver cell may hold clues for treating severe liver disease, according to a recent study from the University of Michigan Life Sciences Institute. The findings, published in ...

The researchers used lipid nanoparticles (LNPs) to deliver cyclic GMP-AMP (cGAMP) synthase (cGAS) mRNA to cancer cells. This results in production of the endogenous stimulator of interferon genes ...

Study identifies citraconate as a metabolic regulator that reverses T cell exhaustion, suppresses lipid-driven toxicity and ...

A key molecular dynamic could be the key to fighting tumors while allowing patients to still receive life-saving cell ...

Dispatch Bio, a biotech company engineering a universal treatment across solid tumors leveraging its first-in-class Flare ...