Cellular metabolism relies on a finely tuned network of transport systems that govern the movement of ions, metabolites and signalling molecules across biological membranes. These systems include ...

Researchers are able to test in parallel the effects of over 1500 active substances on cell metabolism. Their analysis also led to the discovery of previously unknown mechanisms for known medications.

The adult human heart is a reliable, resilient engine fueling our everyday lives while also being responsive enough to ...

Understanding how cells process nutrients and produce energy - collectively known as metabolism - is essential in biology. However, analyzing the vast amounts of data on cellular processes to ...

In a scientific first, researchers from Vanderbilt University and the University of California, San Diego, have generated a high-resolution metabolic "map" of how cells orchestrate glucose processing, ...

Recent lifestyle changes, such as reduced physical activity and increased consumption of energy-dense, processed foods, have ...

When we consume foods containing sugar and starch, they are converted into energy in the body's cells through a process called glycolysis. However, this process has a downside—it produces byproducts ...

A new study published in Science Advances reveals that regular exercise changes metabolism and immune system function down to ...

Aerobic glycolysis dominates lesion bioenergetics, with lactate promoting histone lactylation, M2 macrophage polarization, CD8⁺ T-cell exhaustion, EMT, and fibrosis that reinforce immune-protected ...