The Colts' loss clinched playoff spots for the Bills and Chargers. The 49ers had already clinched their spot in the NFC, and the win keeps them alive for an NFC West title and a shot at the No. 1 seed.

San Francisco cornerback Deommodore Lenoir was fined Saturday by the NFL after his unnecessary roughness penalty in Monday's 49ers win over the Colts.

The San Francisco 49ers offense is cruising and they were dominant in a win over the Indianapolis Colts. Here are the highlights.

By winning Monday night’s final regular-season road game in a 48-27 shootout over the Colts, the 49ers remained in control of their playoff destiny, which could include the NFC’s No. 1 seed for home-field advantage en route to Super Bowl LX at Levi’s Stadium.

Week 16 wraps up with one playoff team and one playoff hopeful. The Niners are rising; the Colts are desperate.

The San Francisco 49ers downed the Indianapolis Colts on Monday night, and here's who deserves credit and criticism.

The Indianapolis Colts are back at home in Week 17 for a divisional matchup with the Jacksonville Jaguars. So who do the NFL experts have winning this game? Now 8-7 on the season, the Colts are barely hanging on to their playoff hopes. In order to make the postseason, the Colts must win out and get some help along the way.

San Francisco 49ers wide receiver Kendrick Bourne hit one of his incentives in his contract during the team's win over the Indianapolis Colts, making $500,000.