Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the G-quadruplex (G4), looks like a knot. These knots can play ...

Two new studies from Johns Hopkins University are providing scientists with an unprecedented view of how human cells repair ...

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions, it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...

After an injury, DNA not only alters its activity but also the way it is organized spatially within the cell nucleus.

Scientists have found unusual four-stranded DNA shapes in human blood plasma. These G-quadruplex structures suggest hidden ...

New research sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells. The study demonstrates how these proteins ...

Scientists show that positively charged metal ions help DNA molecules overcome electrostatic repulsion, supporting the DNA ...

Researchers have found that the way DNA is packaged in cells can directly impact how fast DNA itself is copied during cell division. They discovered that DNA packaging sends signals through an unusual ...

Thymine modified polymer for delivering DNA into cells. A thymine modified compound, poly (ethylene glycol) (PEG), is bound to DNA through an annealing process, then delivered by intramuscular ...

The left-handed spiral of each Z-DNA strand is highlighted on the left. Binding and bonding of the two zinc finger domains (shown in red) from the CTCF protein to Z-DNA (shown in blue). This protein ...