Incidentally identified anomalies within the CNS that are highly suggestive of demyelinating disease have been extensively described in neuropathological series, and are increasingly being detected ...

Demyelinating disorders constitute a diverse group of diseases in which the protective myelin sheath surrounding central nervous system axons is damaged by immune-mediated or inflammatory processes.

People with multiple sclerosis (MS) lose myelin in the gray matter of their brains and the loss is closely correlated with the severity of the disease, according to a new magnetic resonance imaging ...

The term demyelination refers to the loss of the myelin sheath that surrounds and protects axons in the central nervous system. Demyelination occurs as the result of diseases that damage the myelin ...

The idea that multiple sclerosis is a disseminated plaque-like sclerosis was established approximately 150 years ago; indeed, the demonstration of dissemination — in space (disease-related changes in ...

In patients with isolated syndromes that are clinically suggestive of multiple sclerosis, such as optic neuritis or brain-stem or spinal cord syndromes, the presence of lesions as determined by T ...

A 29 year-old woman presented with loss of coordination affecting the right arm and leg. Multiple Sclerosis (MS): (Left and Middle) Flair axial MRIs; (Right) T1-weighted with gadolinium (GAD) axial ...

A new subtype of multiple sclerosis (MS) has been proposed that supports the concept that neurodegeneration and demyelination can occur independently in the disease. Known as myelocortical multiple ...

Teriflunomide treatment incurred an unadjusted risk reduction of 63% and an adjusted risk reduction of 72% in inhibiting a first clinical demyelinating event in patients with multiple sclerosis (MS).

Magnetic resonance imaging (MRI) is the cornerstone of diagnosing and monitoring multiple sclerosis (MS), a chronic autoimmune disease in which the immune system attacks the central nervous system. MS ...