Heming Willis is married to actor Bruce Willis and has been caring for him since he was diagnosed with aphasia in March 2022 and frontotemporal dementia (FTD) in February 2023. Since the diagnosis, Heming Willis has been a vocal advocate for FTD research and often uses her platform to share support for caregivers.

As Bruce Willis lives with frontotemporal dementia, his wife Emma Hemming Willis has become an advocate for others supporting loved ones with longterm care needs.