We often think of our DNA as a nice tightly wound package that exists within the nucleus of the cell. Yet, in various cancers, there are fragments of our genetic code that reside outside of the ...
Cancer therapies can eliminate specific tumors based on their genetic content. However, some cancer cells survive. How do they do it? Part of the answer lies in extrachromosomal DNA (ecDNA), an ace up ...
Extrachromosomal circular DNA (ecDNA) represents a distinct genomic entity that exists independent of the primary chromosomal structure. In cancer, ecDNA is recognised as a potent driver of oncogene ...
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