Fc receptors (FcRs) are a group of glycoproteins that belong to the immunoglobulin superfamily and are classified, like Fc alpha receptors (FcαRs), Fc gamma receptors (FcγRs) and Fc epsilon receptors ...
In therapeutic antibody development the fragment crystallizable (Fc) region is far more than just an antigen-binding aid; it's role is much larger, functioning as the antibody’s functional control ...
An international research group directed by UMC Utrecht has developed and characterized two first-in-class antibodies that ...
Kristi Baker, Shuo-Wang Qiao, Timothy T. Kuo, Victoria G. Aveson, Barbara Platzer, Jan-Terje Andersen, Inger Sandlie, Zhangguo Chen, Colin de Haar, Wayne I. Lencer, Edda Fiebiger, Richard S. Blumberg ...