Researchers corrected the expression of a single overactive gene in the amygdala of mice and reversed anxiety, ...

Scientists have now created an encyclopedia of gene function for all known human genes that code for protein. This data uses the most current and reliable data, and it has also been released on a ...

Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic lateral sclerosis (ALS), offering new hope for treating the devastating ...

Researchers reversed anxiety, depression-like behavior, and social withdrawal in mice by correcting the dosage of a single gene, Grik4, in one population of amygdala neurons. The work, published in ...

Cognitive deficits are a core feature of many neuropsychiatric disorders, including schizophrenia, attention-deficit/hyperactivity disorder and mood disorders. A ...

Cell function is determined by how DNA is expressed into proteins. That process includes two main steps—transcription, when ...

Gene-set analysis seeks to identify the biological mechanisms underlying groups of genes with shared functions. Large language models (LLMs) have shown promise in generating functional descriptions ...

The human heart must constantly adapt to changing demands—a task that requires tightly coordinated molecular shuffling in ...

A comprehensive encyclopedia of the known functions of all protein-coding human genes has just been completed and released. Researchers used large-scale evolutionary modeling to integrate data on ...

A consortium of researchers has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental disorders. These maps detail ...

Researchers at Cornell University have developed a safer and more precise way to study how genes function in living tissues by refining a recently developed CRISPR-based genetic technique in fruit ...