Every embryo of an organism that reproduces sexually faces an early and consequential decision: which of its cell lineages will make up the mortal body, and which will become the germline, the lineage ...

Germ cell development begins with the specification of primordial germ cells (PGCs) in the early embryo, which subsequently migrate to the developing gonads and undergo extensive epigenetic ...

Germ cells, the reproductive cells that eventually become eggs and sperm, are set aside early in embryonic development, when the embryo is just a hollow ball of cells called the gastrula. This means ...