G protein-gated inwardly rectifying K + (GIRK) channels hyperpolarize neurons, reducing membrane excitability. The basal activity of GIRK channels contributes to the resting potential of neurons, ...
Virginia Commonwealth University researchers studying a special class of potassium channels known as GIRKs, which serve important functions in heart and brain tissue, have revealed how they become ...
Bottom Line: Potassium channels play an important role in controlling the electrical activity of neurons in the brain. We identified and characterized a new compound, called GiGA1, that selectively ...
Bottom Line: Potassium channels play an important role in controlling the electrical activity of neurons in the brain. We identified and characterized a new compound, called GiGA1, that selectively ...
Paris, July 12, 2023 – SparingVision ("the Company"), a clinical-stage genomic medicine company developing vision-saving treatments for ocular diseases, today announces that it has sold its ex vivo ...
A key question in protein biochemistry is how proteins recognize "correct" interaction partners in a sea of cellular factors. Nowhere is that more critical to know than in the brain, where ...
Researchers from Columbia University Irving Medical Center published data from a study that assessed GiGA1, a selective G protein-gated inwardly rectifying potassium channel (GIRK) activator, in ...
A group from The Mount Sinai Hospital / Mount Sinai School of Medicine have identified and characterized a novel a GIRK1-selective activator, GiGA1 capable of selectively opening a subset of G-protein ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results