It’s difficult to predict where the system will eventually go because it hasn’t formed yet.

San Francisco 49ers head coach Kyle Shanahan reveals how he’s approaching his division rivals without one of the best players ...

Minneapolis, Minnesota, USA; San Francisco 49ers tight end George Kittle (85) runs after the catch against the Minnesota ...

Kyle Shanahan often couches any comments about the health of his players by noting the obvious: He’s not a doctor. However, ...

Brock Purdy hasn't been quite the same since he lost to the Baltimore Ravens on Christmas. Heading into the game, he was the overwhelming favorite to win the MV ...

ESPN sources: 49ers officially are placing All-Pro RB Christian McCaffrey on injured reserve due to his calf tightness and ...

Now comes the hard part for Kyle Shanahan — devising a game plan without Deebo Samuel and Christian McCaffrey.

The San Francisco 49ers defeated Aaron Rodgers and the New York Jets 32-19 in their season opener at Levi's Stadium last ...

The San Francisco 49ers picked up their first loss of the season, falling 23-17 to the Minnesota Vikings in Week 2.

It was Jordan Mason of all people that carried the San Francisco 49ers to victory over the New York Jets in Week 1. As ...

Even with eight injured players, third-down struggles and troublesome redzone offense in Chapel Hill, 49ers coach Biff Poggi ...

The 49ers struggled against the run in 2023, but that concerned seemed to be in the rearview mirror on Monday.