DNA helicases are motor proteins that translocate along nucleic acids to separate complementary strands, a step essential for replication, repair and recombination. By unwinding duplex DNA and ...

RNA helicases are a group of enzymes that bind to and alter RNA in an ATP-dependent way. They play significant roles in RNA metabolism, gene expression regulation, and innate immunity. Different RNA ...

These are two images showing the structure of the helicase protein complex from above. (a) A surface-rendered three-dimensional electron density map as obtained by cryo-EM. (b) A computer-generated ...

An international research team has determined the first high-resolution structures of the herpes simplex virus origin-binding protein (OBP), a critical component of viral DNA replication that has ...