Occasionally, two research disciplines converge at precisely the right moment and propel each other forward. Such is the case with a screen for growth regulators in acute myeloid leukemia and a small ...

According to the 'classical' view, histone modifications are established in an identical fashion on both copies of each of the four core histones, resulting in 'symmetrically' modified nucleosomes.

Currently, the mammalian heterochromatic proteins HP1α, HP1β and the pan-nuclear HP1γ are considered 'gatekeepers' of methyl-K9-H3-mediated silencing. Understanding how the binding of these proteins ...