Homologous recombination (HR) is a universal DNA repair mechanism that faithfully restores genomic integrity following double-strand breaks (DSBs) in DNA. The details concerning the transfer of ...
When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key repair process called homologous recombination, the cell uses loops in its ...
Menopausal Hormone Therapy and Ovarian and Endometrial Cancers: Long-Term Follow-Up of the Women's Health Initiative Randomized Trials Cancers with homologous recombination deficiency (HRD) can ...
Eight hundred and six patients were randomly assigned (2:1). Tumors were analyzed using the Myriad MyChoice HRD Plus assay to assess non–BRCA HRRm and HRD status; HRD was based on a genomic ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results