A team at Massachusetts General Hospital led by Harvard Medical School physician-scientists has for the second time successfully transplanted a genetically edited pig kidney into a living person. The team performed the first surgery of its kind in the world in March 2024.

Surgeons at Massachusetts General Hospital have successfully performed the fourth pig kidney transplant in the U.S.&nb

It was the fourth pig kidney transplant in the United States, and the first of three that will be done at Mass General as part of a new clinical trial sanctioned by the Food and Drug Administration. Two of the previous patients died shortly after the procedure, including one who was critically ill before the transplant.

The first clinical trials using organs from genetically modified pigs offer hope to patients with kidney failure, who face a long wait for human organ transplants.

Massachusetts General Hospital has transplanted a genetically edited pig kidney into a human for the second time.

With the procedure, Tim Andrews, 66, of Concord, New Hampshire, became the fourth person in the world to receive a genetically-edited pig kidney He was discharged from the hospital on Feb. 1, with his new kidney functioning as expected.

A Mass General Hospital surgical team has completed its second pig-to-human kidney transplant, less than a year after the hospital performed the world’s first such surgery.