The transplant, part of a three-person compassionate use study, used a pig kidney with 69 gene edits provided by U

It was the fourth pig kidney transplant in the United States, and the first of three that will be done at Mass General as part of a new clinical trial sanctioned by the Food and Drug Administration. Two of the previous patients died shortly after the procedure, including one who was critically ill before the transplant.

For the second time in less than a year, doctors at Massachusetts General Hospital have transplanted a genetically-edited pig kidney into a living person. The hospital, which completed the world's first kidney xenotransplantation in March 2024,