Scientists have found a mechanism in the immune systems of mice that can lead to the development of autoimmune disease when turned off. The findings shed light on the processes that lead to the ...

A study by the research team of Prof. Geert van Loo (VIB-UGent Center for Inflammation Research) has unraveled a critical molecular mechanism behind autoimmune and inflammatory diseases such as ...

Scientists have revealed a novel mechanism through which the immune system controls autoimmunity and cancer. In the special focus of the researchers were regulatory T cells -- a type of white blood ...

Scientists at the Icahn School of Medicine at Mount Sinai in New York have identified which parts of the immune system go awry and contribute to autoimmune diseases in individuals with Down syndrome.

The unique role of citrullination in osteoclast differentiation and ACPA-induced osteoclast activation might explain important features of the gradual development of rheumatoid arthritis, including ...

The ability of a human body to resist pathogenic factors is under control of immune cells, the most important of which are lymphocytes. The first subtype called effector lymphocytes, contacts with ...

An autoimmune disorder that affects the thyroid gland, called autoimmune hypothyroidism (AIHT), is the most common autoimmune disease, yet it remains largely understudied. New research from scientists ...

Northwestern Medicine scientists in the laboratory of Stephen Miller, Ph.D., professor emeritus of Microbiology–Immunology, have identified the cellular and molecular mechanisms required for the ...

The available T-cell repertoire — which is modified by interactions with self-peptide–MHC complexes in the thymus and in peripheral tissues — is a key factor in the development of autoimmune disease.

The T-cell branch of the immune system can respond to a virtually infinite variety of antigens, in part because it includes a very large repertoire of T-cell clones, each with a unique receptor for ...

Share on Pinterest Scientists have identified a novel molecular pathway that may link salt intake to MS risk. Ina Peters/Stocksy Multiple sclerosis (MS) is a chronic autoimmune disease caused by the ...