A batch of antiretroviral drug labels has been updated to include Contraindications with an antidepressant. The Food and Drug Administration (FDA) announced that the following antiretroviral drug ...
While off-label use may be permissible, contraindicated use still has a strong regulatory boundary as reinforced by FDA guidance finalized in 2025.
In a recent study published in JAMA Network Open, researchers examined the prevalence of contraindications to nirmatrelvir-ritonavir (Paxlovid) in hospitalized coronavirus disease 2019 (COVID-19) ...