For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside cells. But how these molecular vehicles identify and bind to the right cargo ...

A research team from the University of Osaka, in collaboration with the Massachusetts Institute of Technology, has uncovered a new molecular mechanism underlying chromosome alignment during cell ...

Scientists have long known that inherited neurodegenerative disorders, including Alzheimer's, Parkinson's or motor neuron disease, can be traced back to genetic mutations. However, how they cause the ...

A new study by EPFL scientists shows that age-related decline in motor ability can be countered in fruit flies by enhancing the expression of the protein Trio, suggesting potential treatments for ...

In a recent study published in Nature Communications, researchers combined mass spectrometry-based proteomic phenotyping with machine learning to identify blood biomarkers in early Parkinson's disease ...

Scientists have discovered that a protein once thought to be just a cellular "courier" actually helps plants survive drought. This motor protein, myosin XI, plays a critical role in helping leaves ...

The motion of motor proteins on biopolymers is important for diverse biological processes. Actin, microtubules, and nucleic acids can serve as one-dimensional tracks on which motor proteins move.

DNA-nanoparticle motors are exactly as they sound: tiny artificial motors that use the structures of DNA and RNA to propel motion by enzymatic RNA degradation. Essentially, chemical energy is ...

Cell migration is orchestrated by the coordinated activity of motor proteins and the dynamic rearrangement of cytoskeletal networks. Actin-based motors (principally myosins) convert chemical energy ...

The kinesin-2 motor protein uses a hook-like adaptor and cargo-binding (HAC) domain to recognize and transport cargo along microtubule highways, revealing a cellular logistics system critical for ...