Nature

One-class machine learning classification of skin tissue based on manually scanned optical coherence tomography imaging

Nonmelanoma skin cancers (NMSCs), primarily basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), are the most common cancers in the United States 1. NMSCs can be treated effectively by Mohs ...
Nature

DPAS: disease-associated peptide anomaly score for identifying pathogenic peptides via one-class learning

Predicting disease-associated peptides is a challenging task in bioinformatics, mostly hindered by the lack of reliable negative datasets, leading to biased predictions. In this study, we propose a ...