Eprobe, a highly efficient and reliable fluorescent probe for PCR DNA amplification techniques and DNA analysis in hybridization experiments, has been developed by researchers from RIKEN and Japanese ...

The polymerase chain reaction (PCR) is a common technique used to amplify, or copy, pieces of DNA. Amplified DNA is then used in genetic analyses for everything from medicine to forensics. In plant ...

Testing for COVID-19 continues to be one of the most important tools in the global fight to slow and reduce the impact of the pandemic, particularly until vaccines are more widely available. Regular ...

Quantitative polymerase chain reaction (qPCR) is a molecular technique that has reshaped the landscape of biological research and medicine due to its high sensitivity and specificity. qPCR, also known ...

A DNA strand (purple) primes exponential amplification of DNA (red) as signals for directing light emission of DNA nanodeveices. [Organic and Biomolecular Chemistry] Scientists in Japan say they have ...

Since the discovery of the polymerase chain reaction (PCR) by the oligonucleotide chemist Kary Mullis in 1983, the method has revolutionized molecular biology and clinical diagnostics. Before PCR, DNA ...

Limited sample material and insufficient DNA input pose significant challenges for downstream analysis in various laboratory settings. To overcome this issue, isothermal amplification techniques have ...

Despite its utility, PCR’s main limitation is that it requires precise cycles of heating and cooling to amplify DNA. The thermal cyclers that perform this operation are clunky, relatively expensive, ...

What is multiple cross displacement amplification? Multiple cross displacement amplification (MCDA) method uses random primers and DNA polymerase to amplify the circular DNA template. The DNA can be ...

Scientists have developed a way of amplifying DNA on a scale suitable for use in the emerging fields of DNA-based computing and molecular robotics. By enabling highly sensitive nucleic acid detection, ...

Real-time PCR or quantitative PCR (Polymerase Chain Reaction) is an advancement of the standard PCR technique, which enables continuous monitoring of the reaction and collection of data in real time.