Creative Biolabs Strengthens Liposome and Lipid-Based Drug Delivery Development Solutions with Integrated PK/PD Support

Creative Biolabs provides customized support across key stages of lipid-based therapeutic development, helping researchers optimize delivery systems for different types of therapeutic payloads, ...
ascopubs.org

Pharmacokinetic–pharmacodynamic (PK-PD) modeling and simulation of serdemetan-induced QTc effects in a first-in-human study.

Bioavailability of the hedgehog pathway inhibitor GDC-0449 in a phase I pharmacokinetic (PK) study in healthy female subjects. Background: Serdemetan is a compound that can cause replicative stress ...

Faeth Therapeutics to Present PK/PD Modeling That Informed PIKTOR Dose Selection in Ongoing FTH-PIK-201 Trial at Upcoming Scientific Conference

Faeth Therapeutics (Nasdaq: FTH), a clinical-stage oncology company developing PIKTOR, an investigational all-oral, multi-node inhibitor of the PI3K/AKT/mTOR pathway, will present translational data ...
ascopubs.org

Population pharmacokinetic and pharmacodynamic (PK-PD) parameters of Erwinia Chrysanthemi (ERW) asparaginase (ASNase) using the fused first-order elimination and Michaelis ...

Influence of single agent gemcitabine (GEM) schedule on the pattern of response and toxicity in patients with advanced pancreas, lung and breast carcinoma: A systematic review No significant financial ...
GEN

PK-PD Compass

Developed by the Institute for Clinical Pharmacodynamics, the PK-PD Compass app provides pharmacodynamics (PD) and pharmacokinetics (PK) calculations as they pertain to antibiotics. The goal of this ...
BioWorld

PK/PD analysis of KSP-1007 plus meropenem supports combination treatment

KSP-1007 is a new bicyclic boronate-based broad-spectrum β-lactamase inhibitor that, in combination with meropenem, is under development for the treatment of infections caused by carbapenem-resistant ...