Researchers at the Department of Women's and Children's Health have used a novel technique to map which genes are active in ...

Biological tissues are made up of different cell types arranged in specific patterns, which are essential to their proper functioning. Understanding these spatial arrangements is important when ...

A researcher's guide to spatial transcriptomics: how sequencing- and imaging-based methods work, and how to choose a platform ...

Spatial transcriptomics data analysis increasingly depends on artificial intelligence (AI) to convert raw, location-tagged gene expression readings into a usable map of tissue biology. Unlike ...

Technological development is key to improving the way hematologic cancer is diagnosed and treated. With this vision, the Josep Carreras Leukemia Research Institute is committed to the creation and ...

Applying single-cell RNA sequencing has led researchers to be able to profile the entire transcriptome of cells. However, these transcriptomes prove difficult to link back to their original location ...

Researchers reveal the intricate molecular landscape of triple-negative breast cancer (TNBC), uncovering actionable spatial archetypes and gene signatures that pave the way for personalized therapies ...

Researchers at the Max Delbrück Center have developed an open-source spatial transcriptomics (ST) platform, called Open-ST, that creates 3D molecular maps from patient tissue samples with subcellular ...