Spatial biology captures molecular complexity by preserving the physical context of cells in their native environments. From deciphering RNA dynamics within stress granules to scaling molecular ...

Spatial transcriptomics technologies opened the door for new kinds of biological measurements, allowing scientists to generate detailed maps of where genes are expressed in tissue. But most methods ...

In this collection we highlight a wide range of spatial imaging and spatial omics approaches that enable the spatial visualization of molecular targets in biological tissue. The protocols span between ...

Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located. However, the rapid growth of the technology has come at the cost of ...

Illumina is raising the curtain on its upcoming entry into spatial transcriptomics, with tech designed to help researchers explore cellular behavior mapped across complex tissues. The announcement ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Tumors contain many different types of cells organized in complex spatial patterns that can influence how the disease progresses. Because of this, it is hard to predict how a tumor will develop and ...

Since its inception, spatial biology has proven a revolutionary frontier in life science research. However, there is still plenty of room for growth in the systems we use to conduct spatial biology ...

Scientists at St. Jude Children's Research Hospital, the National Center for Genomic Analysis and the University of Adelaide have created a single-cell RNA analysis method that is 47 times cheaper and ...