Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for therapeutics. Among them, the Y220C mutation is the ninth most frequent and it ...

Clonal hematopoiesis in head and neck carcinomas receiving immunotherapy. Clinical validation of ultra-sensitive WGS-based MRD detection in head and neck squamous cell carcinoma: Results from ...

CAMBRIDGE, MA -- Cancer cells can have thousands of mutations in their DNA. However, only a handful of those actually drive the progression of cancer; the rest are just along for the ride.

To uncover cancer causing mutations in the genome, a team has built a deep neural network that can rapidly scan the entire genome of cancer cells and identify mutations that occur more frequently than ...