Two people infected with the same strain of COVID-19 can have vastly different experiences. One might never even sniffle, and ...
Memorial Sloan Kettering Cancer Center immunologist Santosha Vardhana describes the cruelest part of cancer immunotherapy in one sentence: the treatment seems to be working for a patient, and then it ...
An international panel of 31 experts has published updated 2026 consensus recommendations in The Lancet Rheumatology guiding ...
Chimeric antigen receptor (CAR) T-cell therapies have transformed cancer and autoimmune disease treatment. Modified CAR proteins equip T cells with the ability to identify and eliminate cancer cells ...
The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...
A new type of cancer cell that "warrants urgent investigation" has been discovered in childhood leukemia and could impact clinical care. Research into new or repurposed treatments that target this new ...
Autologous CD19 CAR T products (tisagenlecleucel, axicabtagene ciloleucel, lisocabtagene maraleucel, brexucabtagene autoleucel) show high response rates across ALL and NHL, now including second-line ...