An ad hoc committee of the National Academies of Sciences, Engineering, and Medicine will evaluate the current standards for high-quality systematic reviews for comparative effectiveness research and ...

“Sweet are the uses of adversity, which, like the toad, ugly and venomous, wears yet a precious jewel in his head.” – William Shakespeare, “As You Like It” (II.1.12–17) Despite extensive resilience ...

Obesity is a major health challenge. Here we show that body mass index is positively associated with risk of 19 cancers and inversely associated with 3, based on a systematic review and meta-analysis ...

Objective To evaluate systematic reviews of randomised controlled trials (RCTs) on the effects of exercise on general cognition, memory and executive function across all populations and ages. Methods ...

Grey literature, defined as evidence ‘not controlled by commercial publishers’, can enhance the comprehensiveness, timeliness ...

Objective To examine the comprehensive health impacts of exercise on people with cancer by systematically summarising existing evidence and assessing the strength and reliability of the associations.

Introduction Sepsis is a life-threatening condition in intensive care units (ICUs), where any delay in diagnosis and treatment can lead to organ dysfunction, prolonged hospital stay and increased ...

A systematic review and meta-analysis of 11 randomized controlled trials found that exercise during the post-weight-loss ...