Tropane alkaloids (TAs) are heterocyclic nitrogenous metabolites found across seven orders of angiosperms, including Malpighiales (Erythroxylaceae) and Solanales (Solanaceae). Despite the ...

Researchers report the first successful microbial biosynthesis of the tropane alkaloids hyoscyamine and scopolamine, a class of neuromuscular blockers naturally found in plants in the nightshade ...

Benzylisoquinoline alkaloids (BIAs) represent a diverse group of plant secondary metabolites that are of profound pharmacological importance. These compounds, which include opiates, antimicrobial ...

Plant Physiology, Vol. 174, No. 1 (May 2017), pp. 47-55 (16 pages) Pyrrolizidine alkaloids (PAs) are toxic secondary metabolites that are found in several distantly related families of the angiosperms ...

Complex polycylic structures are found in nearly every biosynthetic class of natural products. In particular, an amazing range of rigid densely functionalized polycylic compounds are formed from ...

The elucidation of the biosynthetic pathway of ipecacuanha alkaloids shows how two distantly related plant species could develop the same substance independently Plants produce an enormous abundance ...

A research team has disclosed the complete biosynthetic pathway for the formation of strychnine in the plant species Strychnos nux-vomica (poison nut). The researchers identified all genes involved in ...

Diego Hidalgo Martinez, Raja S. Payyavula, Chengalrayan Kudithipudi, Yanxin Shen, Dongmei Xu, Ujwala Warek, James A. Strickland and Anastasios Melis Attenuation of nicotine accumulation in Nicotiana ...

Houttuynia cordata, commonly known as yuxingcao, has been a key ingredient in traditional medicine for centuries, valued for its antibiotic-like properties and ability to treat various ailments.

Tropane alkaloids are a particular class of plant derived compounds that have been exploited by mankind since the domestication of medicinal plants. The distribution of these alkaloids is scattered ...

Plants produce an enormous abundance of natural products. Many natural plant products are ancestry-specific and occur only in certain plant families, sometimes only in a single species. Interestingly, ...