The model is also backing Boise State (+10) to cover the spread against Washington in the LA Bowl, while the Over (52.5) hits 53% of the time in Boise State vs. Washington. Before locking in your college football picks for Saturday, Dec. 13, be sure to check out the top college football betting picks from SportsLine's advanced computer model.

Best bets for the opening round of the 2025 College Football Playoff, which features a rematch between Alabama and Oklahoma.

In his 12th season as Penn State's head coach, his team suffered one of the most shocking upsets in college football, falling 42-37 to UCLA as 24.5-point favorites in Week 6. The demoralizing loss for the Nittany Lions ended up being the Bruins' first win on the year.

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The Oklahoma Sooners are currently a slight underdog heading into their College Football Playoff matchup with Alabama.

No. 6 Ole Miss (11-1, 7-1 SEC) will take the field at Vaught-Hemingway Stadium on Dec. 20 in the program's College Football Playoff debut against the Tulane Gre

Kickoff from M&T Bank Stadium is set for 3 p.m. ET on CBS and Paramount+. Navy is a 6-point favorite, according to the latest Army vs. Navy odds. The over/under for total points scored is 38.5. Before making any Navy vs. Army picks, make sure you check out the college football picks from the SportsLine Projection Model.

Betting on bowl games is harder than ever thanks to the new landscape. We spoke to oddsmakers and bettors for their thoughts on the topic.