Endoplasmic reticulum–associated degradation (ERAD) is a cellular protein quality-control process that disposes of proteasomal substrates from the early secretory pathway. Recent work shows that the ...

Three commonly used nonsteroidal anti-inflammatory drugs alter the activity of enzymes within cell membranes, researchers have found. Their finding suggests that, if taken at higher-than-approved ...

Rhomboid domain containing 2 (RHBDD2) was previously observed overexpressed and amplified in breast cancer samples. In order to identify biological pathways modulated by RHBDD2, gene expression ...

Genome sequencing has established the prevalence of 'dead enzymes' — homologues of enzymes that have lost their catalytic sites. These enzymes are expressed and conserved, implying that they have a ...

Rhomboid pain is felt under the neck between the shoulder blades and spine. It’s sometimes referred to as shoulder blade pain or upper back pain. The rhomboid muscle is located in the upper back. It ...