A 28-year-old Middle Eastern man develops severe motor disturbances, including muscle rigidity, tremors, a parkinsonian gait, and involuntary, jerky limb movements, following the administration of a 3 ...

Atypical antipsychotic drugs are less prone to induce extrapyramidal side effects than typical antipsychotics. Distinct pharmacologic profiles, especially actions on 5-hydroxytryptamine (5-HT ...

Addition of the antipsychotic lumateperone (Caplyta) to an existing antidepressant improved symptoms of depression in a ...

Examples of this include benztropine for extrapyramidal symptoms (EPS) of antipsychotics, trazodone or sedative/hypnotics for antidepressant-induced insomnia, modafinil for oversedation of various ...

Presentations include results from two pivotal studies (Studies 501 and 502) evaluating lumateperone as an adjunctive therapy to antidepressants ...

We keen dyslipidemia, EPS sedation, those are the ones where ... assessments are very common in this patient population. Most antipsychotics today recommend lab assessments. So we don't see ...

CAPLYTA Q3 2024 net product sales were $175.2 million, compared to $125.8 million for the same period in 2023, representing a 39% ...

ABSTRACT: Background: Antipsychotic medications are crucial for managing psychiatric disorders such as schizophrenia, but their use can lead to side effects. This study compares the efficacy and side ...

Special Populations: Newborn infants exposed to antipsychotic drugs during the third trimester of pregnancy are at risk for extrapyramidal and/or withdrawal symptoms following delivery.

While antipsychotic Invega Sustenna generated $ ... JNJ's talc products will continue to pressure the stock. “Adjusted EPS guidance has been raised to $10.15, representing a healthy forward ...

Atypical antipsychotics like Invega commonly cause extrapyramidal symptoms (EPS). EPS is a group of side effects that cause a range of movement disorders, specifically involuntary muscle movements.