The bad injury situation exacerbated for the 49ers during the week with multiple downgrades – Colton McKivitz, Charvarius Ward, and Ji’Ayir Brown. Two of those are starting secondary players which would hamper the 49er pass defense. Meanwhile, the Lions got an upgrade with Terrion Arnold.

To make matters worse, offensive lineman Spencer Burford, who was supposed to start at left tackle with Williams and his backup Jaylon Moore on IR for the season, is listed as ‘out’ on the injury report with a calf injury he sustained in the team’s Week 16 loss to the Miami Dolphins.

Spencer Burford officially has been ruled out of San Francisco's Week 17 game against the Detroit Lions on Monday night at Levi's Stadium.

On Monday, the Lions and 49ers will meet in a rematch of last season’s NFC title game at Levi’s Stadium. After holding a 17-point lead at halftime, the Lions fell short of advancing to their first Super Bowl, losing 34-31.

For Lions defensive coordinator Aaron Glenn's money, 49ers star George Kittle is the best tight end in football.

The Lions can clinch the NFC North title with a win over the 49ers on Monday if the Packers upset the Vikings.

The Green Bay Packers are one of the ten teams that has already locked up a spot, but their exact seed remains to be determined. Green Bay could earn the #5 seed if they win out — beating the Minnesota Vikings and Chicago Bears down the stretch — and if the Vikings also lose to the Detroit Lions in week 18.

If the Vikings defeat the Packers on Sunday, then the NFC North will be decided in Week 18 regardless of the outcome of the Lions' game. The Lions have put their sole focus on defeating the 49ers in what is a rematch of last year's NFC Championship game.