LBBP is defined as capturing the left bundle branch (LBB) trunk or its fascicles, whereas capturing only the left septal ...

Cardiac fibroblasts (CF) can become activated and produce excessive extracellular matrix, contributing to fibrotic remodeling ...

Patients with an autoimmune or inflammatory disease (AIID) are at increased cardiovascular risk and may benefit more from statin therapy. In the FOURIER trial (Further Cardiovascular Outcomes Research ...

High-volume physical activity (PA) is associated with a higher prevalence of subclinical coronary artery disease (CAD). However, the clinical significance of subclinical CAD among high-volume ...

Cardiovascular disease remains a leading cause of morbidity and mortality in adults despite recent scientific advancements.

Background: Over-intensification of antihypertensive medication may lead to hypotension and excessive blood pressure (BP) variability and thus increase the risk for falls, a major cause of ...

The growing morbidity, mortality, and health care costs related to heart failure (HF) underscore the urgent need to prioritize its primary prevention. Whereas a risk-based approach for HF prevention ...

Few middle-aged and older adults engage in regular leisure-time exercise. Incidental physical activity (IPA) encompasses activities of daily living outside the leisure-time domain. No dose-response ...

Request permissions for this article. Department of Medicine, UT Southwestern Medical Center, Dallas, TX (M.S.U.). Department of Medicine, Parkland Health and ...