One, and only one, lone pair of electrons from each heteroatom in the ring is part of the aromatic bonding in an azole. Names of azoles maintain the prefix upon reduction (e.g., pyrazoline, pyrazolidine).

Sep 25, 2025 · The azoles that are available for systemic use can be classified into two groups: the triazoles (fluconazole, itraconazole, voriconazole, posaconazole, and isavuconazole) and the …

Azole antifungal agents can be used to treat fungal infections of the body and skin, including athlete's foot, onychomycosis (fungal nail infections), ringworm, and vaginal candidiasis.

Most used antifungal agents are included in the class of azoles. This family of compounds has shown over the decades a vast range of applications in the treatment of fungal infections and diseases, with …

Azoles are nitrogen, sulfur, and oxygen-containing compounds with a five-membered ring system that comprises thiadiazole, oxadiazole, triazole, imidazole, isoxazole, pyrazole, and other rings.

Explore the mechanisms, types, and resistance of azole antifungals in this comprehensive overview.

Aug 28, 2024 · Azoles are synthetic antifungal agents that inhibit fungal growth by targeting ergosterol synthesis, a critical component of the fungal cell membrane. They are categorized into two primary …

Apr 24, 2024 · Azole antifungal medications usually kill A. fumigatus and treat infections, but antifungal resistance can develop after long-term use. Azole fungicides work similarly to kill A. fumigatus that …

The meaning of AZOLE is any of numerous compounds characterized by a 5-membered ring containing at least one nitrogen atom.

m Educational Pearl Know Your Antifungals: Azoles Azoles are one of the four currently available antifungal drug classes.1 The azole antifungal agents include fluconazole, itracona.