One, and only one, lone pair of electrons from each heteroatom in the ring is part of the aromatic bonding in an azole. Names of azoles maintain the prefix upon reduction (e.g., pyrazoline, …

Azole antifungal agents can be used to treat fungal infections of the body and skin, including athlete's foot, onychomycosis (fungal nail infections), ringworm, and vaginal candidiasis.

Sep 25, 2025 · The azoles that are available for systemic use can be classified into two groups: the triazoles (fluconazole, itraconazole, voriconazole, posaconazole, and isavuconazole) and …

Azoles are nitrogen, sulfur, and oxygen-containing compounds with a five-membered ring system that comprises thiadiazole, oxadiazole, triazole, imidazole, isoxazole, pyrazole, and other rings.

m Educational Pearl Know Your Antifungals: Azoles Azoles are one of the four currently available antifungal drug classes.1 The azole antifungal agents include fluconazole, itracona.

Explore the mechanisms, types, and resistance of azole antifungals in this comprehensive overview.

Azoles are a class of antifungal agents that inhibit the synthesis of ergosterol, an essential component of fungal cell membranes. By disrupting ergosterol production, azoles compromise …

May 11, 2025 · Azole antifungals play a central role in the treatment and prevention of fungal infections, offering coverage against yeasts, molds, and dimorphic fungi depending on the agent.

Most used antifungal agents are included in the class of azoles. This family of compounds has shown over the decades a vast range of applications in the treatment of fungal infections and …

Dec 15, 2025 · Azoles are a widely used class of antifungal medications inhibiting the production of ergosterol, a critical component in the fungal cell membrane. The 2 primary subclasses of …