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  1. The Brain’s Waste Disposal System and Why Sleep Is Key for

    Aug 25, 2025 · A growing body of research suggests that the brain clears waste during sleep via the glymphatic system. How does this work and what are the implications for preventing …

  2. Hydrocephalus in an HIV-Infected Patient - Medscape

    Jul 22, 2004 · Inflammatory cells and their byproducts may obstruct CSF flow and absorption, resulting in hydrocephalus. What is the specific underlying cause?

  3. Brain’s Waste Clearance System Implicated in Dementia

    Oct 24, 2025 · Intervening in the pathways that disrupt the brain’s waste clearance system could help prevent or slow Alzheimer’s disease and other dementias.

  4. Low-Flow CSF Shunt Tested in Alzheimer's Disease - Medscape

    Oct. 21, 2002 — Low-flow cerebroventricular shunting may be worth investigating further in Alzheimer's disease, according to the authors of a pilot study reported in the Oct. 22 issue of ...

  5. Brain Clears Toxins During Sleep - Medscape

    Nov 8, 2013 · The researchers infused fluorescent dye into the cerebrospinal fluid (CSF) of mice and observed it flow through the brain.

  6. Paramagnetic Rim Lesions May Aid MS Diagnosis and Treatment

    Mar 3, 2025 · Paramagnetic rim lesions help confirm multiple sclerosis diagnoses and may have prognostic value. New evidence of an immune cell signature could reveal biomarkers and …

  7. Finger-Prick Blood Test Shows Promise for Early AD Detection

    6 days ago · Alzheimer’s disease biomarkers measured from finger-prick dried blood samples closely match standard plasma tests and predict CSF pathology with good accuracy, a large …

  8. Management of Hyperglycemic Crises in Patients With Diabetes

    In some patients, initial cerebrospinal fluid (CSF) chemistry was measured and compared with initial plasma chemistry. It was of interest that HCO 3 and pH in CSF were significantly higher …

  9. FDA Clears First Diagnostic Blood Test for AD - Medscape

    May 16, 2025 · The US Food and Drug Administration (FDA) has granted 510 (k) clearance to the first blood test to aid in diagnosing Alzheimer’s disease (AD).

  10. Decades of Doubt Settled? Shunt Surgery Shows Clear Benefit

    Sep 25, 2025 · A landmark placebo-controlled trial shows shunting improves walking and reduces falls in idiopathic normal-pressure hydrocephalus, challenging decades of skepticism.