Jun 27, 2024 · Valacyclovir treatment may be associated with acute kidney injury, and clinicians should be aware of this and elicit a history of recent exposure to valacyclovir and other nephrotoxins when …

Valacyclovir related acute kidney injury (AKI) is described as a rare side effect. The mechanism of nephrotoxicity includes crystal deposition in the renal tubules resulting in intratubular obstruction and …

Aug 26, 2025 · Common valacyclovir side effects include headaches, nausea, and abdominal pain. While rare, kidney problems, brain-related side effects, and blood disorders are also possible. A few …

Dec 2, 2025 · Valacyclovir is eliminated from the body primarily by the kidneys, where it is converted to its active form, acyclovir. This renal clearance is why patients with compromised kidney function are …

In this case presentation and discussion, we review the presenting symptoms, diagnostic testing, differentials, and pathophysiology regarding crystal-induced AKI, specifically from valacyclovir.

Dec 1, 2025 · However, elderly patients are more likely to have age-related kidney disease, which may require an adjustment in the dose of patients receiving valacyclovir. There are no adequate studies in …

While it is usually safe,1 there have been reports of acute kidney injury associated with this drug.2–8 Clinicians should be aware of the potential for acute kidney injury as an adverse reaction to …

Aug 8, 2019 · Background: Drug-related acute kidney disease is a common side effect of valacyclovir (VACV) treatment.

Aciclovir can accumulate in patients with renal impairment. Therefore, a dose adjustment is needed in these patients to reduce the risk of risk of neurotoxicity. Monitor patients closely for signs of …

May 30, 2025 · Common adverse effects include headache, nausea, and vomiting. A rare adverse effect of valacyclovir is acute kidney injury (AKI) due to obstructive crystal-induced nephropathy, tubular …